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This galley proof is being listed electronically before publishing the final manuscript (It's not final version).

 
Extracellular matrixes and neuroinflammation
Dong Gil Jang1 (Graduate student), Hyo Jung Sim1 (Graduate student), Eun Kyung Song1 (Research worker), Taejoon Kwon1,2 (Professor), Tae Joo Park 1,2,* (Professor)
1School of Life Sciences, Ulsan National Institute of Science and Technology(UNIST), Ulsan, 44919, Republic of Korea,
2Center for Genomic Integrity,, Institute for Basic Science (IBS), Ulsan 44919, Republic of Korea
Abstract
The extracellular matrix is a critical component of every human tissue. ECM not only functions as a structural component but also regulates a variety of cellular processes such as cell migration, differentiation, proliferation, and cell death. In addition, current studies suggest that ECM is critical for the pathophysiology of various human diseases. ECM is composed of diverse components including several proteins and polysaccharide chains such as chondroitin sulfate, heparan sulfate, and hyaluronic acid. Each component of ECM exerts its own functions in cellular and pathophysiological processes. One of the interesting recent findings is that ECM is involved in inflammatory responses in various human tissues. In this review, we summarized the known functions of ECM in neuroinflammation after acute injury and chronic inflammatory diseases of the central nerve systems.
Abstract, Accepted Manuscript(in press) [Submitted on July 23, 2020, Accepted on July 31, 2020]
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